Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKF05718.1Adenylate and Guanylate cyclase catalytic domain protein; KEGG: npu:Npun_R0352 1.7e-197 adenylate/guanylate cyclase. (620 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.900
EKF03994.1
Putative GTP diphosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
EKE98475.1
Ribonucleoside-triphosphate; KEGG: ana:all4035 0. hypothetical protein; K00524 ribonucleotide reductase, class II.
     
  0.900
EKF05263.1
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
     
  0.800
folE
GTP cyclohydrolase I; KEGG: ava:Ava_2537 1.5e-109 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96.
     
  0.800
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
  0.800
folE-2
GTP cyclohydrolase I; KEGG: ana:all4721 3.0e-95 folE; GTP cyclohydrolase I K01495; Psort location: Cytoplasmic, score: 8.96.
     
  0.800
EKF02917.1
Cyclic nucleotide-binding domain protein; KEGG: scl:sce6484 1.3e-14 pp2c12; phosphoprotein phosphatase; Psort location: Cytoplasmic, score: 8.96.
  
 
   0.745
EKF03960.1
Catabolite activator protein; KEGG: eci:UTI89_C3860 1.4e-12 crp; cAMP-regulatory protein K10914.
  
 
   0.709
EKF03765.1
PAS domain S-box; KEGG: ter:Tery_3993 5.0e-60 adenylate/guanylate cyclase; Psort location: CytoplasmicMembrane, score: 9.27.
  
 
   0.704
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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