STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
lysSlysine--tRNA ligase; KEGG: npu:Npun_R5202 1.0e-252 lysyl-tRNA synthetase K04567; Belongs to the class-II aminoacyl-tRNA synthetase family. (508 aa)    
Predicted Functional Partners:
gltX
glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
 
 0.976
argS
arginine--tRNA ligase; KEGG: ana:all3717 6.0e-280 argS; arginyl-tRNA synthetase K01887; Psort location: Cytoplasmic, score: 9.97.
  
 0.974
ileS
isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily.
 
 0.974
proS
proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacy [...]
  
 0.974
EKF03719.1
Hypothetical protein; KEGG: npu:Npun_F6194 6.7e-43 DALR anticodon binding domain-containing protein; Psort location: Cytoplasmic, score: 8.96.
  
 0.967
EKF02266.1
Zinc finger found in FPG and IleRS; KEGG: npu:Npun_F1478 5.2e-09 isoleucyl-tRNA synthetase K01870.
  
 0.966
EKF05368.1
Hypothetical protein; KEGG: ter:Tery_0188 2.7e-14 glutamate--tRNA(Gln) ligase / glutamyl-tRNA synthetase K01885.
  
 0.953
EKF05412.1
Hypothetical protein; KEGG: ter:Tery_0188 5.2e-13 glutamate--tRNA(Gln) ligase / glutamyl-tRNA synthetase K01885; Psort location: CytoplasmicMembrane, score: 9.82.
  
 0.953
metG
methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.953
EKF03987.1
Hypothetical protein; KEGG: ter:Tery_0188 4.3e-11 glutamate--tRNA(Gln) ligase / glutamyl-tRNA synthetase K01885.
  
 0.953
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.