prfC protein (Tolypothrix sp. PCC7601) - STRING interaction network

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prfC

Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (542 aa)

Predicted Functional Partners:

rpmA

0.881

prfA

0.876

rplS

0.837

rplT

0.836

rplM

0.812

rpmJ

0.803

rpmF

0.802

rplQ

0.800

rplI

0.796

rplK

0.788

Your Current Organism:

Tolypothrix sp. PCC7601

NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
prfA	prfC	FDUTEX481_06933	FDUTEX481_01142	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	0.876
prfA	rplI	FDUTEX481_06933	FDUTEX481_09651	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L9; Binds to the 23S rRNA.	0.921
prfA	rplK	FDUTEX481_06933	FDUTEX481_01301	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.868
prfA	rplM	FDUTEX481_06933	FDUTEX481_06936	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.977
prfA	rplQ	FDUTEX481_06933	FDUTEX481_06938	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L17; KEGG: bxe:Bxe_B1353 0.065 putative acetyltransferase protein K00680; Psort location: Cytoplasmic, score: 9.97.	0.967
prfA	rplS	FDUTEX481_06933	FDUTEX481_01305	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L19 splS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.949
prfA	rplT	FDUTEX481_06933	FDUTEX481_09351	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.951
prfA	rpmA	FDUTEX481_06933	FDUTEX481_03400	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L27; KEGG: rca:Rcas_4308 0.62 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; K00860 adenylylsulfate kinase K00958; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL27 family.	0.954
prfA	rpmF	FDUTEX481_06933	FDUTEX481_09697	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L32; KEGG: bra:BRADO5576 0.031 folA; dihydrofolate reductase K00287; Belongs to the bacterial ribosomal protein bL32 family.	0.897
prfA	rpmJ	FDUTEX481_06933	FDUTEX481_06942	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	Ribosomal protein L36; KEGG: cag:Cagg_2818 0.94 deoxyribose-phosphate aldolase K01619; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL36 family.	0.890
prfC	prfA	FDUTEX481_01142	FDUTEX481_06933	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.	0.876
prfC	rplI	FDUTEX481_01142	FDUTEX481_09651	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L9; Binds to the 23S rRNA.	0.796
prfC	rplK	FDUTEX481_01142	FDUTEX481_01301	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.788
prfC	rplM	FDUTEX481_01142	FDUTEX481_06936	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.812
prfC	rplQ	FDUTEX481_01142	FDUTEX481_06938	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L17; KEGG: bxe:Bxe_B1353 0.065 putative acetyltransferase protein K00680; Psort location: Cytoplasmic, score: 9.97.	0.800
prfC	rplS	FDUTEX481_01142	FDUTEX481_01305	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L19 splS; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.	0.837
prfC	rplT	FDUTEX481_01142	FDUTEX481_09351	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.	0.836
prfC	rpmA	FDUTEX481_01142	FDUTEX481_03400	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L27; KEGG: rca:Rcas_4308 0.62 bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein; K00860 adenylylsulfate kinase K00958; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL27 family.	0.881
prfC	rpmF	FDUTEX481_01142	FDUTEX481_09697	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L32; KEGG: bra:BRADO5576 0.031 folA; dihydrofolate reductase K00287; Belongs to the bacterial ribosomal protein bL32 family.	0.802
prfC	rpmJ	FDUTEX481_01142	FDUTEX481_06942	Peptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.	Ribosomal protein L36; KEGG: cag:Cagg_2818 0.94 deoxyribose-phosphate aldolase K01619; Psort location: Cytoplasmic, score: 9.26; Belongs to the bacterial ribosomal protein bL36 family.	0.803

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