STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKF05033.1Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (394 aa)    
Predicted Functional Partners:
EKF05898.1
KEGG: npu:Npun_R0059 2.8e-99 riboflavin synthase, alpha subunit; K00793 riboflavin synthase alpha chain; Psort location: Cytoplasmic, score: 9.26.
  
 0.999
ribBA
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
 0.999
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
 
 0.995
EKF06211.1
GTP cyclohydrolase II; KEGG: rop:ROP_03890 1.5e-157 putative GTP cyclohydrolase II; Psort location: Cytoplasmic, score: 8.96.
 
 0.972
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
   0.932
EKF04823.1
Hypothetical protein; KEGG: vvy:VVA0006 1.3e-23 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II.
 
    
 0.917
EKF05496.1
Hypothetical protein; KEGG: vpa:VPA0006 8.9e-25 GTP cyclohydrolase II; K01497 GTP cyclohydrolase II.
 
    
 0.917
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
    
 0.915
EKF06212.1
Hypothetical protein; KEGG: ppp:PHYPADRAFT_108913 0.95 hypothetical protein; K01915 glutamine synthetase; Psort location: Cytoplasmic, score: 8.96.
  
 
 0.877
EKF01119.1
KEGG: npu:Npun_F0943 2.3e-129 riboflavin biosynthesis protein RibF K11753; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.735
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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