STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKF05152.1Hydrolase, NUDIX family; KEGG: npu:Npun_F5834 5.9e-67 NUDIX hydrolase; Belongs to the Nudix hydrolase family. (164 aa)    
Predicted Functional Partners:
EKE96598.1
Hydrolase, NUDIX family; KEGG: ote:Oter_1043 4.7e-42 NUDIX hydrolase; K03574 7,8-dihydro-8-oxoguanine triphosphatase; Psort location: Cytoplasmic, score: 8.96.
  
     0.734
hisI
KEGG: npu:Npun_F4098 6.9e-105 phosphoribosyl-AMP cyclohydrolase K11755; Psort location: Cytoplasmic, score: 9.97; In the N-terminal section; belongs to the PRA-CH family.
     
 0.562
mutM
formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
     
 0.561
EKF00068.1
Recombination protein J; KEGG: npu:Npun_R4754 0. single-stranded-DNA-specific exonuclease RecJ; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.555
EKE99431.1
Recombination protein J; KEGG: ana:all1989 0. recJ; single-strand-DNA-specific exonuclease; K07462 single-stranded-DNA-specific exonuclease; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.555
EKF05151.1
Hydrolase, alpha/beta fold family protein; KEGG: ava:Ava_1799 1.7e-94 alpha/beta hydrolase fold K01563.
       0.480
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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