STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hslOChaperonin HslO; Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress. (301 aa)    
Predicted Functional Partners:
EKE99706.1
Hypothetical protein; KEGG: dps:DP1240 0.052 cysteine synthase A; K01738 cysteine synthase A.
  
  
 0.707
EKF04968.1
Putative fibronectin-binding protein; KEGG: mpt:Mpe_A3065 0.051 flgJ; flagellum-specific muramidase K02395.
  
     0.697
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
  
  
 0.694
EKF04672.1
Hypothetical protein; KEGG: sat:SYN_01800 0.015 ribosomal large subunit pseudouridine synthase D K06180; Psort location: Cytoplasmic, score: 8.96.
  
     0.651
coaX
Transcriptional regulator; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
    0.581
EKE97140.1
Chaperone HtpG; KEGG: eci:UTI89_C0501 6.3e-63 htpG; heat shock protein 90 K04079.
   
  
 0.554
mutS2
MutS family DNA mismatch repair protein; Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity; Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.
  
   
 0.548
EKF01713.1
Hypothetical protein; KEGG: mrd:Mrad2831_3544 0.0038 ribulose-phosphate 3-epimerase K03687.
   
  
 0.546
EKF05350.1
Hypothetical protein; KEGG: ava:Ava_1592 5.8e-07 serine/threonine protein kinase K00908.
       0.540
EKE99592.1
Ribosome biogenesis GTP-binding protein YlqF; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.
 
    0.527
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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