Crossover junction forming protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.

Excision endonuclease subunit UvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dis [...]

Ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.

Crossover junction forming protein; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.

Integrase; KEGG: sph:MGAS10270_Spy0789 0.96 nth; endonuclease III K10773; Psort location: Cytoplasmic, score: 8.96; Belongs to the 'phage' integrase family.

Excision endonuclease subunit UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.

Putative integrase; KEGG: ccv:CCV52592_1299 0.23 ATP synthase C chain (lipid-binding protein)(dicyclohexylcarbodiimide-binding protein).

Putative 5-methylcytosine; KEGG: eco:b4345 5.8e-07 mcrC, ECK4335, JW5789; 5-methylcytosine-specific restriction enzyme McrBC, subunit McrC; Psort location: Cytoplasmic, score: 8.96.

Putative integrase; KEGG: sph:MGAS10270_Spy0789 0.64 nth; endonuclease III K10773; Psort location: Cytoplasmic, score: 8.96; Belongs to the 'phage' integrase family.