STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
EKF04457.1ATP-dependent DNA helicase; KEGG: cgl:NCgl0704 9.8e-42 cgl0735; putative helicase K01529; Psort location: Cytoplasmic, score: 8.96. (688 aa)    
Predicted Functional Partners:
EKF04456.1
DEAD/DEAH box family helicase; KEGG: hwa:HQ3274A 5.2e-75 helicase K01529; Psort location: CytoplasmicMembrane, score: 9.82.
 
     0.946
EKF00393.1
KEGG: npu:Npun_R3585 0. ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: Cytoplasmic, score: 9.97.
  
 0.941
topA
DNA topoisomerase TopA; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA s [...]
 
 
 0.898
EKF01112.1
ATP-dependent helicase RecQ; KEGG: npu:Npun_F0932 4.3e-215 ATP-dependent DNA helicase RecQ; K03654 ATP-dependent DNA helicase RecQ; Psort location: CytoplasmicMembrane, score: 8.46.
  
 0.884
EKE99775.1
Replicative DNA helicase DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
   
 0.880
topA-2
DNA topoisomerase; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA superc [...]
   
 0.843
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
   
 0.840
EKF00488.1
Hypothetical protein; KEGG: ame:724599 0.20 similar to Chromodomain-helicase-DNA-binding protein CG3733-PA; K11367 chromodomain-helicase-DNA-binding protein 1; Psort location: Cytoplasmic, score: 8.96.
   
 0.840
EKF05537.1
SNF2 family helicase; KEGG: hsl:OE8016F 7.2e-28 ATP-dependent helicase; Psort location: Cytoplasmic, score: 8.96.
 
 
 
 0.825
EKE97885.1
KEGG: ava:Ava_C0075 2.0e-226 DNA polymerase III beta subunit family protein K02338; Psort location: Cytoplasmic, score: 9.97.
   
 0.801
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.