close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKF03505.1Hypothetical protein; KEGG: mpe:MYPE2780 0.31 ruvB; Holliday junction DNA helicase RuvB K03551; Psort location: Cytoplasmic, score: 8.96. (451 aa)    
Predicted Functional Partners:
EKF03506.1
Hypothetical protein; KEGG: aci:ACIAD3384 0.00039 putative sulfate permease; K01673 carbonic anhydrase; Psort location: CytoplasmicMembrane, score: 10.00.
 
     0.647
EKF03504.1
Hypothetical protein; KEGG: edi:EDI_048910 7.9e-12 intracellular protein transport protein USO1; Psort location: Cytoplasmic, score: 8.96.
       0.559
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.511
EKF01290.1
KEGG: npu:Npun_R0978 1.2e-118 prephenate dehydrogenase K00210.
 
     0.473
argB
Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily.
 
     0.427
EKF03107.1
Putative tetratricopeptide-repeat protein; KEGG: ppp:PHYPADRAFT_151528 0.045 hypothetical protein; K09561 STIP1 homology and U-box containing protein 1.
  
     0.421
EKF02290.1
Putative FeS-containing Cyanobacterial-specific oxidoreductase; KEGG: bta:508875 0.10 TP53I3; tumor protein p53 inducible protein 3; K10133 tumor protein p53-inducible protein 3; Psort location: Cytoplasmic, score: 8.96.
  
     0.401
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.