STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKF03518.1KEGG: npu:Npun_F6461 4.8e-200 isochorismate synthase K02552; Psort location: Cytoplasmic, score: 9.26. (471 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
 0.998
EKE99922.1
Non-ribosomal peptide synthetase; KEGG: npu:Npun_R3431 0. amino acid adenylation domain-containing protein; Psort location: CytoplasmicMembrane, score: 8.46.
  
  
 0.985
EKF01185.1
KEGG: npu:Npun_F1347 3.5e-94 glutamine amidotransferase of anthranilate synthase K01658; Psort location: Cytoplasmic, score: 9.97.
  
  
 0.957
EKE97447.1
AMP-binding enzyme; KEGG: ava:Ava_1613 0. non-ribosomal peptide synthase.
  
  
 0.956
EKF06121.1
AMP-binding enzyme; KEGG: npu:Npun_R3431 1.6e-248 amino acid adenylation domain-containing protein.
  
  
 0.921
EKF03257.1
AMP-binding enzyme; KEGG: ava:Ava_1613 0. non-ribosomal peptide synthase; Psort location: CytoplasmicMembrane, score: 8.46.
  
  
 0.921
EKE97866.1
AMP-binding enzyme; KEGG: npu:Npun_R6588 0. amino acid adenylation domain-containing protein; Psort location: Cytoplasmic, score: 9.97; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 0.921
EKE97842.1
Thioesterase domain protein; KEGG: npu:Npun_R5497 5.2e-75 amino acid adenylation domain-containing protein; Psort location: Cytoplasmic, score: 9.26.
  
  
 0.921
EKE97162.1
Hypothetical protein; KEGG: ttu:TERTU_4529 0.0058 ubiC; 4-hydroxybenzoate synthetase.
     
 0.913
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.911
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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