STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKF03437.1KEGG: ava:Ava_2749 3.5e-140 serine/threonine dehydratase K01754; Psort location: Cytoplasmic, score: 8.96. (330 aa)    
Predicted Functional Partners:
ilvD-2
KEGG: npu:Npun_R3783 3.2e-274 dihydroxy-acid dehydratase K01687; Belongs to the IlvD/Edd family.
 
 0.874
ilvD
KEGG: ava:Ava_0023 1.7e-268 dihydroxy-acid dehydratase K01687; Psort location: Cytoplasmic, score: 8.96; Belongs to the IlvD/Edd family.
 
 0.869
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
  
 0.829
EKF03438.1
Hypothetical protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.752
EKF05079.1
GMP synthase; KEGG: ava:Ava_1294 0. glutamate synthase (ferredoxin) K00284.
  
 
 0.719
EKF05179.1
KEGG: fta:FTA_1583 1.7e-23 endoribonuclease L-PSP K07567.
 
 
 0.654
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.647
EKF00650.1
Aminotransferase, class IV; KEGG: npu:Npun_F4880 4.6e-108 aminotransferase, class IV K00826.
  
 
 0.615
EKF05098.1
Acetolactate synthase, small subunit; KEGG: ava:Ava_2035 9.6e-83 ilvH; acetolactate synthase 3 regulatory subunit K01653.
  
 
 0.605
EKF05783.1
Acetolactate synthase; KEGG: ana:all3555 9.1e-277 ilvB; acetolactate synthase; K01652 acetolactate synthase I/II/III large subunit; Psort location: Cytoplasmic, score: 9.97; Belongs to the TPP enzyme family.
 
 
 0.595
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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