STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKF04063.1Glutathione-disulfide reductase; Maintains high levels of reduced glutathione. (459 aa)    
Predicted Functional Partners:
EKE99123.1
Branched-chain alpha-keto acid dehydrogenase subunit E2; KEGG: npu:Npun_F6414 1.4e-193 dehydrogenase catalytic domain-containing protein K00627; Psort location: Cytoplasmic, score: 9.26.
 0.995
EKF04985.1
Putative pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
 
 0.982
EKF02564.1
Glutaredoxin; KEGG: cyp:PCC8801_0474 1.0e-103 glutaredoxin-family domain protein.
 
 
 0.954
gshB
Glutathione synthase; KEGG: npu:Npun_F4803 1.2e-146 glutathione synthetase K01920; Belongs to the prokaryotic GSH synthase family.
  
  
 0.949
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
  
 0.946
EKF00450.1
KEGG: npu:Npun_F3527 2.2e-85 glutathione S-transferase domain-containing protein K00799; Psort location: Cytoplasmic, score: 9.97; Belongs to the GST superfamily.
  
  
 0.931
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.929
EKF02556.1
KEGG: npu:Npun_R4660 4.7e-67 glutathione peroxidase K00432; Belongs to the glutathione peroxidase family.
   
 0.919
EKF02684.1
KEGG: npu:Npun_F6084 9.1e-87 glutathione S-transferase domain-containing protein; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.917
EKF03223.1
KEGG: mpt:Mpe_A3285 3.9e-47 putative glutathione S-transferase; K00799 glutathione S-transferase; Belongs to the GST superfamily.
  
  
 0.915
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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