Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKE99274.1N-6 DNA methylase; KEGG: aci:ACIAD3432 1.1e-168 putative type I restriction-modification system DNA methylase (HsdM); K03427 type I restriction enzyme M protein; Psort location: Cytoplasmic, score: 8.96. (520 aa)    
Predicted Functional Partners:
EKE99278.1
KEGG: cyp:PCC8801_3940 5.8e-92 restriction modification system DNA specificity domain protein; K01154 type I restriction enzyme, S subunit; Psort location: Cytoplasmic, score: 8.96.
 0.995
EKF05526.1
Putative type I site-specific deoxyribonuclease specificity subunit; KEGG: glo:Glov_0844 5.6e-87 restriction endonuclease S subunits-like protein; K01154 type I restriction enzyme, S subunit.
 
 0.941
EKE97099.1
Hypothetical protein; KEGG: rci:RCIX1320 1.4e-17 hsdS-2; type I restriction modification system, specificity subunit K01154; Psort location: Cytoplasmic, score: 8.96.
  
 0.932
EKF00498.1
KEGG: tye:THEYE_A1693 7.2e-52 restriction endonuclease S subunit; K01154 type I restriction enzyme, S subunit; Psort location: Cytoplasmic, score: 8.96.
  
 0.932
EKE99282.1
typeI site-specific deoxyribonuclease; KEGG: aeh:Mlg_1789 0. type III restriction enzyme, res subunit; K01153 type I restriction enzyme, R subunit; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.926
EKF00497.1
KEGG: tye:THEYE_A1697 0. type I site-specific deoxyribonuclease; K01153 type I restriction enzyme, R subunit; Psort location: Cytoplasmic, score: 8.96.
  
 0.901
EKF05527.1
Type I site-specific deoxyribonuclease restriction subunit; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.714
EKE99888.1
KEGG: hmo:HM1_3070 4.0e-51 hsdR; type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit; Psort location: Cytoplasmic, score: 8.96.
 
  
 0.672
EKE98171.1
Hypothetical protein; KEGG: chl:Chy400_1964 1.2e-16 type I site-specific deoxyribonuclease, HsdR family; K01153 type I restriction enzyme, R subunit.
 
  
 0.653
uvrB
Excision endonuclease subunit UvrB; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dis [...]
    
  0.651
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.