STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKE99288.1Putative magnesium transporter; Acts as a magnesium transporter. (300 aa)    
Predicted Functional Partners:
EKE98932.1
Divalent cation transporter; KEGG: pmt:PMT0126 4.1e-36 Mg2+ transporter K06213; Psort location: CytoplasmicMembrane, score: 10.00.
     0.985
guaA
GMP synthase protein; Catalyzes the synthesis of GMP from XMP.
    
 0.813
EKF00569.1
Sensor histidine kinase; KEGG: ava:Ava_0198 3.0e-246 multi-sensor hybrid histidine kinase K00936; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.736
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.565
EKF06106.1
5'-nucleotidase protein; KEGG: ava:Ava_3996 3.3e-215 metallophosphoesterase K01081; Psort location: Periplasmic, score: 9.76; Belongs to the 5'-nucleotidase family.
    
  0.546
EKF05079.1
GMP synthase; KEGG: ava:Ava_1294 0. glutamate synthase (ferredoxin) K00284.
    
  0.542
purH
KEGG: npu:Npun_R6316 3.4e-229 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase K00602; Psort location: Cytoplasmic, score: 8.96.
    
 0.541
EKF04101.1
Peptidase, M23 family; KEGG: npu:Npun_F6078 6.8e-224 peptidase M23B; Psort location: OuterMembrane, score: 8.86.
   
  0.532
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.530
EKF03635.1
Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
    
  0.524
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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