STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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queF7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (134 aa)    
Predicted Functional Partners:
queC
Adenosine nucleotide-binding protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
 
 
 0.996
EKF05037.1
6-pyruvoyl tetrahydropterin synthase/QueD family protein; KEGG: ana:alr0080 1.6e-57 hypothetical protein; K01737 6-pyruvoyl tetrahydrobiopterin synthase.
 
  
 0.856
queE
Radical SAM domain protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
  
 0.844
EKF01340.1
Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.
  
  
 0.844
EKE98546.1
Queuosine biosynthesis protein QueD; KEGG: npu:Npun_F2811 9.8e-145 putative 6-pyruvoyl tetrahydropterin synthase; K01737 6-pyruvoyl tetrahydrobiopterin synthase; Psort location: Cytoplasmic, score: 8.96.
  
  
 0.821
queA
S-adenosylmethionine_tRNA- isomerase queA protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).
 
  
 0.708
tgt
tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...]
    
 0.684
EKE98895.1
Cadmium resistance transporter family protein; KEGG: hip:CGSHiEE_05500 0.80 pgi; glucose-6-phosphate isomerase; Psort location: CytoplasmicMembrane, score: 10.00.
   
    0.630
EKE98897.1
Cadmium resistance transporter family protein; KEGG: pan:PoanfMp07 0.32 cox3; cytochrome c oxidase subunit 3 K02262; Psort location: CytoplasmicMembrane, score: 10.00.
   
    0.630
EKE97821.1
Cadmium resistance transporter family protein; KEGG: ctj:JALI_5391 0.996 dnaQ2; DNA polymerase III, epsilon chain; K02342 DNA polymerase III subunit epsilon; Psort location: CytoplasmicMembrane, score: 10.00.
   
    0.630
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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