STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EKE98755.1Response regulator; KEGG: pmf:P9303_26471 2.1e-94 rpaA; two-component response regulator K10697; Psort location: Cytoplasmic, score: 9.97. (247 aa)    
Predicted Functional Partners:
sasA
Putative sensor histidine kinase; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
  
 
 0.977
sigA
DNA-directed RNA polymerase sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.853
rpoA
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
   0.853
rpoZ
DNA-directed RNA polymerase; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
 
   0.827
EKF02965.1
Sensor histidine kinase; KEGG: npu:Npun_F2908 0. multi-sensor hybrid histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.812
EKF01257.1
Sensor histidine kinase; KEGG: cyn:Cyan7425_1795 8.8e-247 PAS/PAC sensor hybrid histidine kinase; Psort location: CytoplasmicMembrane, score: 7.88.
  
 
 0.812
EKF02293.1
Sensor histidine kinase; KEGG: ava:Ava_0647 6.5e-299 multi-sensor signal transduction histidine kinase K00936; Psort location: CytoplasmicMembrane, score: 10.00.
 
 
 0.808
EKE98428.1
Sensor histidine kinase; KEGG: ava:Ava_1564 3.7e-276 multi-sensor hybrid histidine kinase K00936; Psort location: CytoplasmicMembrane, score: 9.99.
  
 
 0.799
EKE99368.1
Sensor histidine kinase; KEGG: ava:Ava_1564 0. multi-sensor hybrid histidine kinase K00936; Psort location: CytoplasmicMembrane, score: 9.99.
  
 
 0.799
EKE99007.1
Sensor histidine kinase; KEGG: cyc:PCC7424_1141 6.2e-104 integral membrane sensor signal transduction histidine kinase; Psort location: CytoplasmicMembrane, score: 10.00.
  
 
 0.796
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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