STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mdhMalate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (335 aa)    
Predicted Functional Partners:
EKE99680.1
Putative type II citrate synthase; KEGG: ava:Ava_2713 1.2e-187 citrate synthase K01647; Psort location: Cytoplasmic, score: 9.97.
  
 0.999
EKE96610.1
ACT domain protein; KEGG: npu:Npun_F1023 3.5e-220 malic enzyme, NAD-binding K00027; Psort location: Cytoplasmic, score: 8.96.
  
 0.990
EKF03010.1
Isocitrate dehydrogenase, NADP-dependent; KEGG: ana:alr1827 5.6e-245 icd; isocitrate dehydrogenase K00031; Psort location: Cytoplasmic, score: 9.97.
  
 0.985
atpA
ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.
  
 0.974
EKF05784.1
KEGG: npu:Npun_R4631 5.1e-212 aldehyde dehydrogenase K00135; Psort location: Cytoplasmic, score: 9.26.
    
 0.952
ppc
Phosphoenolpyruvate carboxykinase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
     
 0.951
EKE97400.1
KEGG: ava:Ava_3046 0. ferredoxin (flavodoxin) oxidoreductase K03737.
  
  
 0.950
EKF00361.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
  
  
 0.950
EKF03415.1
Pyruvate kinase; KEGG: npu:Npun_F4277 6.8e-288 pyruvate kinase K00873; Psort location: Cytoplasmic, score: 8.96.
  
 0.946
EKF06230.1
Aspartate transaminase; KEGG: npu:Npun_R0187 1.4e-191 aminotransferase, class I and II K00812; Psort location: Cytoplasmic, score: 9.97.
   
 0.941
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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