Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EKE97406.1Coproporphyrinogen dehydrogenase; KEGG: npu:Npun_R4584 4.1e-210 oxygen-independent coproporphyrinogen III oxidase; K02495 oxygen-independent coproporphyrinogen III oxidase; Psort location: Cytoplasmic, score: 9.97; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (460 aa)    
Predicted Functional Partners:
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.952
EKF05547.1
Hypothetical protein; KEGG: rcm:A1E_05665 7.1e-16 coproporphyrinogen III oxidase K08973; Psort location: CytoplasmicMembrane, score: 10.00.
    
 0.931
hemF
Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
    
 0.921
hemF-2
Coproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
    
 0.921
EKE99352.1
KEGG: ava:Ava_4393 1.4e-131 coproporphyrinogen III oxidase K02495; Psort location: Cytoplasmic, score: 9.97.
  
  
 
0.901
EKF05867.1
Pyridine nucleotide-disulfide oxidoreductase; KEGG: ava:Ava_3378 1.4e-145 sulfide-quinone reductase K00540; Psort location: CytoplasmicMembrane, score: 9.27.
  
    0.597
EKE97405.1
Heme oxygenase; KEGG: npu:Npun_R4585 1.6e-89 heme oxygenase K00510.
     
 0.586
EKE97400.1
KEGG: ava:Ava_3046 0. ferredoxin (flavodoxin) oxidoreductase K03737.
     
 0.571
EKF00361.1
Pyruvate:ferredoxin (flavodoxin) oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin.
     
 0.571
EKF05079.1
GMP synthase; KEGG: ava:Ava_1294 0. glutamate synthase (ferredoxin) K00284.
     
 0.506
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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