EKF01964.1 protein (Tolypothrix sp. PCC7601)

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Predicted Interactions

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Score

EKF01964.1

KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44. (713 aa)

Predicted Functional Partners:

EKF04151.1

0.790

EKF00436.1

0.703

EKF01424.1

0.678

EKE98552.1

0.533

EKE98767.1

0.531

EKF06241.1

0.526

EKF02906.1

0.475

EKE99059.1

0.465

EKF00420.1

0.450

EKF03205.1

0.445

Your Current Organism:

Tolypothrix sp. PCC7601

NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EKE98552.1	EKF01964.1	FDUTEX481_03856	FDUTEX481_07215	KEGG: ava:Ava_0316 0. peptidase M1, membrane alanine aminopeptidase K01256; Psort location: Cytoplasmic, score: 9.97.	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	0.533
EKE98767.1	EKF01964.1	FDUTEX481_03765	FDUTEX481_07215	Alpha/beta hydrolase; KEGG: bpm:BURPS1710b_A1076 2.2e-10 hypothetical protein K01044.	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	0.531
EKE99059.1	EKF00436.1	FDUTEX481_03251	FDUTEX481_09099	MAPEG family protein; KEGG: syn:sll1147 1.0e-37 glutathione S-transferase; K00799 glutathione S-transferase; Psort location: CytoplasmicMembrane, score: 10.00.	KEGG: cts:Ctha_1266 2.6e-12 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 8.96.	0.548
EKE99059.1	EKF01964.1	FDUTEX481_03251	FDUTEX481_07215	MAPEG family protein; KEGG: syn:sll1147 1.0e-37 glutathione S-transferase; K00799 glutathione S-transferase; Psort location: CytoplasmicMembrane, score: 10.00.	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	0.465
EKE99059.1	EKF06241.1	FDUTEX481_03251	FDUTEX481_00179	MAPEG family protein; KEGG: syn:sll1147 1.0e-37 glutathione S-transferase; K00799 glutathione S-transferase; Psort location: CytoplasmicMembrane, score: 10.00.	KEGG: npu:Npun_R2728 1.4e-90 succinylglutamate desuccinylase/aspartoacylase K01437; Psort location: Cytoplasmic, score: 8.96; Belongs to the AspA/AstE family. Aspartoacylase subfamily.	0.458
EKF00420.1	EKF01964.1	FDUTEX481_09082	FDUTEX481_07215	Transposase; KEGG: ssc:396816 0.90 ALR2; aldose reductase K00011.	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	0.450
EKF00436.1	EKE99059.1	FDUTEX481_09099	FDUTEX481_03251	KEGG: cts:Ctha_1266 2.6e-12 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 8.96.	MAPEG family protein; KEGG: syn:sll1147 1.0e-37 glutathione S-transferase; K00799 glutathione S-transferase; Psort location: CytoplasmicMembrane, score: 10.00.	0.548
EKF00436.1	EKF01964.1	FDUTEX481_09099	FDUTEX481_07215	KEGG: cts:Ctha_1266 2.6e-12 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 8.96.	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	0.703
EKF00436.1	EKF06241.1	FDUTEX481_09099	FDUTEX481_00179	KEGG: cts:Ctha_1266 2.6e-12 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 8.96.	KEGG: npu:Npun_R2728 1.4e-90 succinylglutamate desuccinylase/aspartoacylase K01437; Psort location: Cytoplasmic, score: 8.96; Belongs to the AspA/AstE family. Aspartoacylase subfamily.	0.674
EKF01424.1	EKF01964.1	FDUTEX481_08074	FDUTEX481_07215	Hypothetical protein; KEGG: sax:USA300HOU_0932 0.083 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	0.678
EKF01964.1	EKE98552.1	FDUTEX481_07215	FDUTEX481_03856	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	KEGG: ava:Ava_0316 0. peptidase M1, membrane alanine aminopeptidase K01256; Psort location: Cytoplasmic, score: 9.97.	0.533
EKF01964.1	EKE98767.1	FDUTEX481_07215	FDUTEX481_03765	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	Alpha/beta hydrolase; KEGG: bpm:BURPS1710b_A1076 2.2e-10 hypothetical protein K01044.	0.531
EKF01964.1	EKE99059.1	FDUTEX481_07215	FDUTEX481_03251	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	MAPEG family protein; KEGG: syn:sll1147 1.0e-37 glutathione S-transferase; K00799 glutathione S-transferase; Psort location: CytoplasmicMembrane, score: 10.00.	0.465
EKF01964.1	EKF00420.1	FDUTEX481_07215	FDUTEX481_09082	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	Transposase; KEGG: ssc:396816 0.90 ALR2; aldose reductase K00011.	0.450
EKF01964.1	EKF00436.1	FDUTEX481_07215	FDUTEX481_09099	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	KEGG: cts:Ctha_1266 2.6e-12 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; K00384 thioredoxin reductase (NADPH); Psort location: Cytoplasmic, score: 8.96.	0.703
EKF01964.1	EKF01424.1	FDUTEX481_07215	FDUTEX481_08074	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	Hypothetical protein; KEGG: sax:USA300HOU_0932 0.083 acyltransferase; Psort location: CytoplasmicMembrane, score: 10.00.	0.678
EKF01964.1	EKF02906.1	FDUTEX481_07215	FDUTEX481_05708	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	Hypothetical protein; KEGG: xop:PXO_04446 3.0e-07 tRNA nucleotidyltransferase; K00974 tRNA nucleotidyltransferase (CCA-adding enzyme); Psort location: Cytoplasmic, score: 8.96.	0.475
EKF01964.1	EKF03205.1	FDUTEX481_07215	FDUTEX481_05486	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	Type I secretion target GGXGXDXXX repeat-containing domain protein; KEGG: ava:Ava_4160 1.3e-41 VCBS K01317; Psort location: Extracellular, score: 9.44.	0.445
EKF01964.1	EKF04151.1	FDUTEX481_07215	FDUTEX481_02791	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	Animal heme peroxidase; KEGG: osa:4352160 1.9e-102 Os12g0448900; hypothetical protein; K10529 alpha-dioxygenase.	0.790
EKF01964.1	EKF06241.1	FDUTEX481_07215	FDUTEX481_00179	KEGG: npu:Npun_F6548 9.7e-123 lipoxygenase-like protein; Psort location: Periplasmic, score: 9.44.	KEGG: npu:Npun_R2728 1.4e-90 succinylglutamate desuccinylase/aspartoacylase K01437; Psort location: Cytoplasmic, score: 8.96; Belongs to the AspA/AstE family. Aspartoacylase subfamily.	0.526

page 1 of 2

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.895

expected number of edges:

11

PPI enrichment p-value:

1.9e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 100

1.34

2.22

1.96e-10

GO:0009059

Macromolecule biosynthetic process

11 of 164

1.17

1.72

1.96e-10

GO:0010467

Gene expression

11 of 187

1.11

1.57

1.96e-10

GO:0044271

Cellular nitrogen compound biosynthetic process

11 of 244

1.0

1.26

1.51e-09

GO:0044238

Primary metabolic process

11 of 736

0.52

0.45

0.00011

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 55

1.6

3.41

7.00e-13

GO:0019843

rRNA binding

8 of 41

1.64

3.03

5.68e-10

GO:0003723

RNA binding

9 of 99

1.3

1.97

4.42e-09

GO:0070180

Large ribosomal subunit rRNA binding

2 of 2

2.34

1.08

0.0103

GO:0000049

tRNA binding

3 of 24

1.44

0.83

0.0156

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 57

1.59

3.45

1.16e-13

GO:0044391

Ribosomal subunit

4 of 14

1.8

2.22

9.87e-06

GO:0015934

Large ribosomal subunit

3 of 8

1.92

1.89

0.00012

GO:0032991

Protein-containing complex

5 of 143

0.89

0.69

0.0026

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:27330141

(2016) Whole genomic DNA sequencing and comparative genomic analysis of Arthrospira platensis: high genome plasticity and genetic diversity.

7 of 26

1.78

2.96

3.35e-08

PMID:28977619

(2017) The stability of an mRNA is influenced by its concentration: a potential physical mechanism to regulate gene expression.

8 of 51

1.54

2.45

3.35e-08

PMID:22043294

(2011) Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.

4 of 8

2.04

1.98

0.00011

PMID:20019804

(2009) Transcriptome and proteome exploration to model translation efficiency and protein stability in Lactococcus lactis.

6 of 65

1.31

1.32

0.00015

PMID:30779773

(2019) Multiplexing polysome profiling experiments to study translation in Escherichia coli.

3 of 7

1.98

1.24

0.0040

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:95

rRNA-binding

8 of 31

1.76

3.73

1.37e-11

CL:86

Ribosome, and Translational elongation

11 of 69

1.55

3.38

1.30e-14

CL:89

Ribosome

10 of 59

1.57

3.36

2.01e-13

CL:91

Ribosome

9 of 50

1.6

3.28

4.05e-12

CL:147

Large ribosomal subunit rRNA binding, and Translation regulation

4 of 5

2.25

3.03

9.25e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

llm03010

Ribosome

10 of 55

1.6

3.53

9.24e-14

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0015934

Large ribosomal subunit

5 of 10

2.04

3.23

1.01e-07

GOCC:0005840

Ribosome

8 of 45

1.59

2.87

9.60e-10

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 6

2.04

1.94

0.00013

GOCC:0043229

Intracellular organelle

10 of 224

0.99

1.19

5.88e-08

GOCC:0032991

Protein-containing complex

6 of 331

0.6

0.38

0.0297

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 56

1.6

3.45

2.01e-13

KW-0699

rRNA-binding

8 of 39

1.66

3.24

9.68e-11

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