STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EKE99294.1Hypothetical protein; KEGG: fjo:Fjoh_1014 0.97 dihydroneopterin aldolase; K01633 dihydroneopterin aldolase; Psort location: Extracellular, score: 9.64. (120 aa)    
Predicted Functional Partners:
EKE99295.1
KEGG: tet:TTHERM_00257190 0.70 TPR Domain containing protein; Psort location: CytoplasmicMembrane, score: 9.82.
       0.693
EKF04417.1
PAS domain S-box; KEGG: ava:Ava_C0117 0. serine/threonine protein kinase and signal transduction histidine kinase with GAF and PAS/PAC sensor K00903; Psort location: CytoplasmicMembrane, score: 10.00.
   
  0.664
EKF03000.1
ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein; KEGG: ava:Ava_2845 1.6e-153 serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF and PAS/PAC sensor; Psort location: CytoplasmicMembrane, score: 7.88.
    
  0.635
EKE96861.1
PAS domain S-box; KEGG: ava:Ava_2845 0. serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF and PAS/PAC sensor; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.635
EKF00826.1
Hypothetical protein; KEGG: ava:Ava_3995 6.6e-44 serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF sensor K00908.
    
  0.635
EKF00053.1
PAS domain S-box; KEGG: ava:Ava_2845 0. serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF and PAS/PAC sensor; Psort location: CytoplasmicMembrane, score: 9.99.
    
  0.635
EKF00069.1
PAS domain S-box; KEGG: ava:Ava_2845 0. serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF and PAS/PAC sensor; Psort location: CytoplasmicMembrane, score: 10.00.
    
  0.635
gyrB
DNA topoisomerase; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.628
EKF05717.1
Adenylate and Guanylate cyclase catalytic domain protein; KEGG: ava:Ava_4489 0. serine/threonine protein kinase and signal transduction histidine kinase with GAF sensor K00908; Psort location: CytoplasmicMembrane, score: 9.99.
   
  0.494
EKF04952.1
GAF domain protein; KEGG: ava:Ava_3596 0. serine/threonine protein kinase and signal transduction histidine kinase (STHK) with GAF sensor K00908.
    
  0.459
Your Current Organism:
Tolypothrix sp. PCC7601
NCBI taxonomy Id: 1188
Other names: Calothrix sp. PCC 7601, Fremyella diplosiphon ACMM 396, Fremyella diplosiphon IAM M-100, Fremyella diplosiphon UTEX B 481, Microchaete diplosiphon UTEX B 481, T. sp. PCC 7601, Tolypothrix (Calothrix) sp. PCC 7601, Tolypothrix sp. PCC 7601, Tolypothrix sp. PCC 7601 = UTEX B 481
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.