STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAPyruvate dehydrogenase E1 subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (369 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 subunit beta.
 0.999
pdhC
Dihydrolipoamide S-acetyltransferase.
 0.999
pdhD
Dihydrolipoamide dehydrogenase.
 
 0.999
lplA
Lipoate-protein ligase A.
  
 
 0.974
ldh
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 
 0.972
tktA
Transketolase.
  
 
 0.965
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.962
pgi
Glucose-6-phosphate isomerase (GPI).
    
 0.960
fba
Fructose-bisphosphate aldolase.
    
 0.959
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.
    
  0.949
Your Current Organism:
Mycoplasma auris
NCBI taxonomy Id: 1188233
Other names: M. auris 15026, Mycoplasma auris 15026
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