STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiIThiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (384 aa)    
Predicted Functional Partners:
pheT
Phenylalanyl-tRNA synthetase beta chain (PheT).
  
  
 0.602
trmU
tRNA(5-methylaminomethyl-2-thiouridylate)- methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
  
 
 0.595
parC
Topoisomerase IV subunit A.
  
    0.504
parE
Topoisomerase IV subunit B.
  
    0.503
truB
tRNA pseudouridine synthase B; Belongs to the pseudouridine synthase TruB family.
   
  
 0.488
nusG
Transcription antitermination protein; Participates in transcription elongation, termination and antitermination.
  
    0.448
metG
Methionyl-tRNA synthetase.
  
  
 0.441
secE
Hypothetical protein, putative SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.
       0.417
polA
DNA polymerase I: 5'-3' exonuclease domain protein.
  
    0.414
rpmG1
50S ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
       0.408
Your Current Organism:
Mycoplasma auris
NCBI taxonomy Id: 1188233
Other names: M. auris 15026, Mycoplasma auris 15026
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.