STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaGDNA primase. (626 aa)    
Predicted Functional Partners:
polA
DNA polymerase I, 5'-3' exonuclease.
  
 
 0.999
rpoD
RNA polymerase sigma-A factor rpoD.
  
 0.994
dnaB-1
Replicative DNA helicase.
 
 0.968
dnaB-2
Replicative DNA helicase.
 
 0.967
engA
GTP-binding protein EngA.
  
    0.822
glyS
Glycyl-tRNA synthetase.
  
    0.810
topA
DNA topoisomerase I.
  
  
 0.785
nfo
Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin.
       0.751
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
  
  
 0.638
metS
Methionyl-tRNA synthetase (Methionine-tRNAligase, MetRS).
  
  
 0.637
Your Current Organism:
Mycoplasma alkalescens
NCBI taxonomy Id: 1188234
Other names: M. alkalescens 14918, Mycoplasma alkalescens 14918
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.