STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
topADNA topoisomerase I. (614 aa)    
Predicted Functional Partners:
leuS
Leucyl-tRNA synthetase.
   
 
 0.999
recA
Recombinase A.
  
 0.977
rpoA
DNA-directed RNA polymerase alpha chain.
   
 
 0.968
polA
DNA polymerase I, 5'-3' exonuclease.
  
 0.961
ssb
Single-strand binding protein.
  
 
 0.954
ssb-2
Single-strand binding protein.
  
 
 0.954
ligA
NAD(+)-dependent DNA ligase.
   
 
 0.944
rpoC
DNA-directed RNA polymerase beta' chain.
  
 
 0.935
dnaN
DNA polymerase III beta chain.
   
 0.935
pcrA
ATP-dependent helicase.
  
 
 0.935
Your Current Organism:
Mycoplasma alkalescens
NCBI taxonomy Id: 1188234
Other names: M. alkalescens 14918, Mycoplasma alkalescens 14918
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.