STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
polADNA polymerase I, 5'-3' exonuclease. (291 aa)    
Predicted Functional Partners:
dnaG
DNA primase.
  
 
 0.999
dnaN
DNA polymerase III beta chain.
  
 0.999
recA
Recombinase A.
  
 0.999
potA
Spermidine/putrescine ABC transporter ATP-binding protein potA.
  
 0.988
mutM
Foramidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
  
  
 0.970
dnaE
DNA polymerase III alpha subunit.
  
 
 0.966
topA
DNA topoisomerase I.
  
 0.961
dinP
DNA polymerase IV (DinB).
  
 0.953
pcrA
ATP-dependent helicase.
   
 
 0.942
acpP
Putative acyl carrier protein.
  
 0.906
Your Current Organism:
Mycoplasma alkalescens
NCBI taxonomy Id: 1188234
Other names: M. alkalescens 14918, Mycoplasma alkalescens 14918
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.