node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MBVG_0980 | MBVG_3940 | MBVG_0980 | MBVG_3940 | Hypothetical protein; Belongs to the NAPRTase family. | 5'Nucleotidase, predicted lipoprotein; Belongs to the 5'-nucleotidase family. | 0.918 |
MBVG_0980 | nadD | MBVG_0980 | MBVG_3170 | Hypothetical protein; Belongs to the NAPRTase family. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.981 |
MBVG_0980 | nadE | MBVG_0980 | MBVG_3080 | Hypothetical protein; Belongs to the NAPRTase family. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.482 |
MBVG_3940 | MBVG_0980 | MBVG_3940 | MBVG_0980 | 5'Nucleotidase, predicted lipoprotein; Belongs to the 5'-nucleotidase family. | Hypothetical protein; Belongs to the NAPRTase family. | 0.918 |
MBVG_3940 | nadD | MBVG_3940 | MBVG_3170 | 5'Nucleotidase, predicted lipoprotein; Belongs to the 5'-nucleotidase family. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.912 |
MBVG_4030 | nadD | MBVG_4030 | MBVG_3170 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.669 |
MBVG_4030 | obg | MBVG_4030 | MBVG_1620 | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.629 |
coaD | nadD | MBVG_1760 | MBVG_3170 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.599 |
glyA | nadD | MBVG_1540 | MBVG_3170 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.590 |
mucB | nadD | MBVG_3180 | MBVG_3170 | DNA-damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.832 |
mucB | nifS | MBVG_3180 | MBVG_3200 | DNA-damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | Nitrogen fixation protein NifS. | 0.819 |
mucB | nifU | MBVG_3180 | MBVG_3190 | DNA-damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | Nitrogen fixation protein NifU. | 0.812 |
nadD | MBVG_0980 | MBVG_3170 | MBVG_0980 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Hypothetical protein; Belongs to the NAPRTase family. | 0.981 |
nadD | MBVG_3940 | MBVG_3170 | MBVG_3940 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 5'Nucleotidase, predicted lipoprotein; Belongs to the 5'-nucleotidase family. | 0.912 |
nadD | MBVG_4030 | MBVG_3170 | MBVG_4030 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | GTP-binding protein; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.669 |
nadD | coaD | MBVG_3170 | MBVG_1760 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.599 |
nadD | glyA | MBVG_3170 | MBVG_1540 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.590 |
nadD | mucB | MBVG_3170 | MBVG_3180 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | DNA-damage repair protein MucB; Belongs to the DNA polymerase type-Y family. | 0.832 |
nadD | nadE | MBVG_3170 | MBVG_3080 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. | 0.982 |
nadD | nifS | MBVG_3170 | MBVG_3200 | Bidomainal protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | Nitrogen fixation protein NifS. | 0.828 |