STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldh-1L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. (315 aa)    
Predicted Functional Partners:
pyk
Pyruvate kinase (PK); Belongs to the pyruvate kinase family.
  
 0.985
pgiB
Glucose-6-phosphate isomerase; Belongs to the GPI family.
  
 
 0.975
pdhB
Pyruvate dehydrogenase E1 component, beta subunit.
  
 0.971
fba
Fructose-bisphosphate aldolase (Fba).
   
 
 0.967
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.965
ldh-2
L-lactate dehydrogenase.
  
  
 
0.945
fusA
Elongation factor G (EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
   
 
 0.794
fba-2
Fructose-bisphosphate aldolase class-II.
   
 
 0.781
tsf
Elongation factor Ts (ET-Ts); Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family.
  
  
 0.757
tkt-1
Transketolase; Belongs to the transketolase family.
  
 0.755
Your Current Organism:
Mycoplasma ovipneumoniae
NCBI taxonomy Id: 1188239
Other names: M. ovipneumoniae 14811, Mycoplasma ovipneumoniae 14811
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