STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
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[Homology]
Score
fabH3-oxoacyl-[acyl-carrier-protein] synthase 3; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)    
Predicted Functional Partners:
SAMN04488119_11112
Malonyl CoA-acyl carrier protein transacylase.
 
 0.998
plsX
Phosphate acyltransferase; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.
 
  
 0.997
SAMN04488119_10690
Biotin carboxyl carrier protein of acetyl-CoA carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.991
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family.
 
 
 0.990
SAMN04488119_104207
Acyl transferase domain-containing protein.
  
 
 0.990
SAMN04488119_11115
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
 0.990
SAMN04488119_10639
Nodulation protein E; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.989
SAMN04488119_101213
3-oxoacyl-[acyl-carrier-protein] synthase-1; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
 0.987
accA
Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.
 
 
 0.969
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.
 
  
 0.967
Your Current Organism:
Oceanicella actignis
NCBI taxonomy Id: 1189325
Other names: Amaricoccus sp. CLW, CGMCC 1.10808 [[Pleomorphobacterium xiamenense]], DSM 22673, DSM 24423 [[Pleomorphobacterium xiamenense]], LMG 25334, LMG 26245 [[Pleomorphobacterium xiamenense]], LMG:25334, LMG:26245 [[Pleomorphobacterium xiamenense]], MCCC 1A06272 [[Pleomorphobacterium xiamenense]], O. actignis, Oceanicella actignis Albuquerque et al. 2012, Pleomorphobacterium xiamenense, Pleomorphobacterium xiamenense Yin et al. 2013, Rhodobacteraceae bacterium CLW, Rhodobacteraceae bacterium PRQ-67, Rhodobacteraceae bacterium PRQ-68, strain CLW [[Pleomorphobacterium xiamenense]], strain PRQ-67
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