STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAMN04488119_1061023-carboxy-cis,cis-muconate cycloisomerase. (458 aa)    
Predicted Functional Partners:
SAMN04488119_106104
Protocatechuate 3,4-dioxygenase alpha subunit.
 
 
 0.996
SAMN04488119_106105
Protocatechuate 3,4-dioxygenase beta subunit.
 
 
 0.996
SAMN04488119_106106
annotation not available
 
 
 0.996
SAMN04488119_106107
3-oxoadipate enol-lactonase.
 
 0.979
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 0.942
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Belongs to the SAICAR synthetase family.
 
 0.921
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase.
  
 0.912
purD
Phosphoribosylamine--glycine ligase; Belongs to the GARS family.
  
 0.904
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
  
 0.895
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.881
Your Current Organism:
Oceanicella actignis
NCBI taxonomy Id: 1189325
Other names: Amaricoccus sp. CLW, CGMCC 1.10808 [[Pleomorphobacterium xiamenense]], DSM 22673, DSM 24423 [[Pleomorphobacterium xiamenense]], LMG 25334, LMG 26245 [[Pleomorphobacterium xiamenense]], LMG:25334, LMG:26245 [[Pleomorphobacterium xiamenense]], MCCC 1A06272 [[Pleomorphobacterium xiamenense]], O. actignis, Oceanicella actignis Albuquerque et al. 2012, Pleomorphobacterium xiamenense, Pleomorphobacterium xiamenense Yin et al. 2013, Rhodobacteraceae bacterium CLW, Rhodobacteraceae bacterium PRQ-67, Rhodobacteraceae bacterium PRQ-68, strain CLW [[Pleomorphobacterium xiamenense]], strain PRQ-67
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