Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A3SI_03043 | dut | A3SI_03043 | A3SI_03048 | Hypothetical protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.793 |
| A3SI_04367 | A3SI_06359 | A3SI_04367 | A3SI_06359 | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Cmp/dcmp deaminase zinc-binding protein; COG2131 Deoxycytidylate deaminase. | 0.709 |
| A3SI_04367 | A3SI_11809 | A3SI_04367 | A3SI_11809 | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | 0.403 |
| A3SI_04367 | A3SI_11819 | A3SI_04367 | A3SI_11819 | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | 0.403 |
| A3SI_04367 | dut | A3SI_04367 | A3SI_03048 | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.719 |
| A3SI_04367 | tdk | A3SI_04367 | A3SI_05362 | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | COG1435 Thymidine kinase. | 0.739 |
| A3SI_04367 | thyA | A3SI_04367 | A3SI_08421 | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.995 |
| A3SI_06359 | A3SI_04367 | A3SI_06359 | A3SI_04367 | Cmp/dcmp deaminase zinc-binding protein; COG2131 Deoxycytidylate deaminase. | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.709 |
| A3SI_06359 | adk | A3SI_06359 | A3SI_02156 | Cmp/dcmp deaminase zinc-binding protein; COG2131 Deoxycytidylate deaminase. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.628 |
| A3SI_06359 | dut | A3SI_06359 | A3SI_03048 | Cmp/dcmp deaminase zinc-binding protein; COG2131 Deoxycytidylate deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.751 |
| A3SI_06359 | tdk | A3SI_06359 | A3SI_05362 | Cmp/dcmp deaminase zinc-binding protein; COG2131 Deoxycytidylate deaminase. | COG1435 Thymidine kinase. | 0.701 |
| A3SI_06359 | thyA | A3SI_06359 | A3SI_08421 | Cmp/dcmp deaminase zinc-binding protein; COG2131 Deoxycytidylate deaminase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.732 |
| A3SI_06944 | adk | A3SI_06944 | A3SI_02156 | Putative deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. | 0.734 |
| A3SI_06944 | dut | A3SI_06944 | A3SI_03048 | Putative deoxyribonucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.765 |
| A3SI_11584 | dut | A3SI_11584 | A3SI_03048 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.870 |
| A3SI_11584 | thyA | A3SI_11584 | A3SI_08421 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.832 |
| A3SI_11809 | A3SI_04367 | A3SI_11809 | A3SI_04367 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.403 |
| A3SI_11809 | A3SI_11819 | A3SI_11809 | A3SI_11819 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | 0.638 |
| A3SI_11809 | dut | A3SI_11809 | A3SI_03048 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.711 |
| A3SI_11819 | A3SI_04367 | A3SI_11819 | A3SI_04367 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; COG0452 Phosphopantothenoylcysteine synthetase/decarboxylase; overlaps another CDS with the same product name. | Dihydrofolate reductase subunit; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | 0.403 |
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