| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CAP_0065 | CAP_0066 | CAP_0065 | CAP_0066 | 5,10-methylenetetrahydrofolate reductase. | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. | 0.589 |
| CAP_0065 | CAP_0067 | CAP_0065 | CAP_0067 | 5,10-methylenetetrahydrofolate reductase. | Hemolysins and protein containing CBS domain protein. | 0.441 |
| CAP_0065 | purH | CAP_0065 | CAP_8958 | 5,10-methylenetetrahydrofolate reductase. | IMP cyclohydrolase. | 0.434 |
| CAP_0066 | CAP_0065 | CAP_0066 | CAP_0065 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. | 5,10-methylenetetrahydrofolate reductase. | 0.589 |
| CAP_0066 | CAP_0067 | CAP_0066 | CAP_0067 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. | Hemolysins and protein containing CBS domain protein. | 0.587 |
| CAP_0067 | CAP_0065 | CAP_0067 | CAP_0065 | Hemolysins and protein containing CBS domain protein. | 5,10-methylenetetrahydrofolate reductase. | 0.441 |
| CAP_0067 | CAP_0066 | CAP_0067 | CAP_0066 | Hemolysins and protein containing CBS domain protein. | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. | 0.587 |
| CAP_0067 | CAP_1794 | CAP_0067 | CAP_1794 | Hemolysins and protein containing CBS domain protein. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.401 |
| CAP_0067 | CAP_5359 | CAP_0067 | CAP_5359 | Hemolysins and protein containing CBS domain protein. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.414 |
| CAP_0067 | guaA | CAP_0067 | CAP_8105 | Hemolysins and protein containing CBS domain protein. | GMP synthase/glutamine-hydrolyzing protein; Catalyzes the synthesis of GMP from XMP. | 0.871 |
| CAP_0067 | purH | CAP_0067 | CAP_8958 | Hemolysins and protein containing CBS domain protein. | IMP cyclohydrolase. | 0.406 |
| CAP_0067 | ybeY | CAP_0067 | CAP_3099 | Hemolysins and protein containing CBS domain protein. | Metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.615 |
| CAP_1794 | CAP_0067 | CAP_1794 | CAP_0067 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hemolysins and protein containing CBS domain protein. | 0.401 |
| CAP_1794 | CAP_5359 | CAP_1794 | CAP_5359 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.923 |
| CAP_1794 | guaA | CAP_1794 | CAP_8105 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | GMP synthase/glutamine-hydrolyzing protein; Catalyzes the synthesis of GMP from XMP. | 0.977 |
| CAP_1794 | purH | CAP_1794 | CAP_8958 | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | IMP cyclohydrolase. | 0.579 |
| CAP_5359 | CAP_0067 | CAP_5359 | CAP_0067 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Hemolysins and protein containing CBS domain protein. | 0.414 |
| CAP_5359 | CAP_1794 | CAP_5359 | CAP_1794 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.923 |
| CAP_5359 | guaA | CAP_5359 | CAP_8105 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | GMP synthase/glutamine-hydrolyzing protein; Catalyzes the synthesis of GMP from XMP. | 0.956 |
| CAP_5359 | purH | CAP_5359 | CAP_8958 | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | IMP cyclohydrolase. | 0.941 |