CAP_1111 protein (Chondromyces apiculatus) - STRING interaction network

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CAP_1111

5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (518 aa)

Predicted Functional Partners:

CAP_2075

0.997

metK

0.990

ahcY

0.988

CAP_2498

0.982

CAP_7783

0.961

CAP_7003

0.958

metG

0.941

CAP_6766

0.918

CAP_5195

0.912

CAP_5574

0.880

Your Current Organism:

Chondromyces apiculatus

NCBI taxonomy Id: 1192034
Other names: C. apiculatus DSM 436, Chondromyces apiculatus Cm a2, Chondromyces apiculatus DSM 436, Chondromyces apiculatus str. DSM 436, Chondromyces apiculatus strain DSM 436

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAP_1111	CAP_2075	CAP_1111	CAP_2075	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	5,10-methylenetetrahydrofolate reductase.	0.997
CAP_1111	CAP_2498	CAP_1111	CAP_2498	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.982
CAP_1111	CAP_5195	CAP_1111	CAP_5195	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Homocysteine S-methyltransferase.	0.912
CAP_1111	CAP_5574	CAP_1111	CAP_5574	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Homoserine dehydrogenase.	0.880
CAP_1111	CAP_6766	CAP_1111	CAP_6766	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Cystathionine beta-synthase.	0.918
CAP_1111	CAP_7003	CAP_1111	CAP_7003	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	O-acetylhomoserine sulfhydrylase.	0.958
CAP_1111	CAP_7783	CAP_1111	CAP_7783	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Cystathionine gamma-lyase.	0.961
CAP_1111	ahcY	CAP_1111	CAP_3363	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.988
CAP_1111	metG	CAP_1111	CAP_5787	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.941
CAP_1111	metK	CAP_1111	CAP_4552	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.990
CAP_2075	CAP_1111	CAP_2075	CAP_1111	5,10-methylenetetrahydrofolate reductase.	5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.	0.997
CAP_2075	CAP_2498	CAP_2075	CAP_2498	5,10-methylenetetrahydrofolate reductase.	5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.999
CAP_2075	CAP_5195	CAP_2075	CAP_5195	5,10-methylenetetrahydrofolate reductase.	Homocysteine S-methyltransferase.	0.963
CAP_2075	CAP_5574	CAP_2075	CAP_5574	5,10-methylenetetrahydrofolate reductase.	Homoserine dehydrogenase.	0.988
CAP_2075	CAP_6766	CAP_2075	CAP_6766	5,10-methylenetetrahydrofolate reductase.	Cystathionine beta-synthase.	0.993
CAP_2075	CAP_7003	CAP_2075	CAP_7003	5,10-methylenetetrahydrofolate reductase.	O-acetylhomoserine sulfhydrylase.	0.997
CAP_2075	CAP_7783	CAP_2075	CAP_7783	5,10-methylenetetrahydrofolate reductase.	Cystathionine gamma-lyase.	0.997
CAP_2075	ahcY	CAP_2075	CAP_3363	5,10-methylenetetrahydrofolate reductase.	Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.	0.964
CAP_2075	metG	CAP_2075	CAP_5787	5,10-methylenetetrahydrofolate reductase.	Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.	0.999
CAP_2075	metK	CAP_2075	CAP_4552	5,10-methylenetetrahydrofolate reductase.	S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.	0.991

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