CAP_2000 protein (Chondromyces apiculatus) - STRING interaction network

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Score

CAP_2000

2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (163 aa)

Predicted Functional Partners:

CAP_5427

0.999

CAP_2832

0.998

CAP_2439

0.981

ribB

0.960

CAP_1893

0.946

CAP_9013

0.881

CAP_7081

0.766

CAP_5036

0.756

CAP_7811

0.756

CAP_1794

0.692

Your Current Organism:

Chondromyces apiculatus

NCBI taxonomy Id: 1192034
Other names: C. apiculatus DSM 436, Chondromyces apiculatus Cm a2, Chondromyces apiculatus DSM 436, Chondromyces apiculatus str. DSM 436, Chondromyces apiculatus strain DSM 436

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAP_1794	CAP_2000	CAP_1794	CAP_2000	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	0.692
CAP_1794	CAP_2439	CAP_1794	CAP_2439	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	GTP cyclohydrolase I.	0.840
CAP_1794	CAP_2832	CAP_1794	CAP_2832	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Dihydroneopterin aldolase.	0.685
CAP_1794	CAP_5427	CAP_1794	CAP_5427	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.724
CAP_1794	CAP_9013	CAP_1794	CAP_9013	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.	0.534
CAP_1794	ribB	CAP_1794	CAP_2888	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.588
CAP_1893	CAP_2000	CAP_1893	CAP_2000	Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	0.946
CAP_1893	CAP_2439	CAP_1893	CAP_2439	Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	GTP cyclohydrolase I.	0.965
CAP_1893	ribB	CAP_1893	CAP_2888	Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.999
CAP_2000	CAP_1794	CAP_2000	CAP_1794	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.692
CAP_2000	CAP_1893	CAP_2000	CAP_1893	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Hypothetical protein; Belongs to the GTP cyclohydrolase I type 2/NIF3 family.	0.946
CAP_2000	CAP_2439	CAP_2000	CAP_2439	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	GTP cyclohydrolase I.	0.981
CAP_2000	CAP_2832	CAP_2000	CAP_2832	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Dihydroneopterin aldolase.	0.998
CAP_2000	CAP_5036	CAP_2000	CAP_5036	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	tRNA nucleotidyltransferase.	0.756
CAP_2000	CAP_5427	CAP_2000	CAP_5427	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.	0.999
CAP_2000	CAP_7081	CAP_2000	CAP_7081	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Anthranilate synthase, aminase component.	0.766
CAP_2000	CAP_7811	CAP_2000	CAP_7811	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Poly(A) polymerase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.	0.756
CAP_2000	CAP_9013	CAP_2000	CAP_9013	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	Dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.	0.881
CAP_2000	ribB	CAP_2000	CAP_2888	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase.	3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.	0.960
CAP_2439	CAP_1794	CAP_2439	CAP_1794	GTP cyclohydrolase I.	Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.	0.840

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