close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAP_41062-oxoglutarate dehydrogenase E1 component. (976 aa)    
Predicted Functional Partners:
CAP_8904
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 0.999
CAP_6079
Dihydrolipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex.
 0.996
CAP_6159
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.996
CAP_2178
Dihydrolipoamide dehydrogenase of pyruvate dehydrogenase complex.
  
 0.994
CAP_6601
Glutamate synthase [NADPH] large chain.
     
 0.994
CAP_7431
2-oxo acid dehydrogenase acyltransferase catalytic domain protein.
 
 0.994
CAP_3742
Isocitrate dehydrogenase.
   
 
 0.992
sucC
Succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.984
sucD
Succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.969
CAP_1285
Soluble pyridine nucleotide transhydrogenase.
 
 0.966
Your Current Organism:
Chondromyces apiculatus
NCBI taxonomy Id: 1192034
Other names: C. apiculatus DSM 436, Chondromyces apiculatus Cm a2, Chondromyces apiculatus DSM 436, Chondromyces apiculatus str. DSM 436, Chondromyces apiculatus strain DSM 436
Server load: very high (>100%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.