close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icmFB12 binding domain / kinase domain / Methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. (1152 aa)    
Predicted Functional Partners:
CAP_4653
Methylmalonyl-CoA mutase.
 
0.999
CAP_1339
Malonyl CoA-acyl carrier protein transacylase.
    
 0.989
CAP_7832
Citrate synthase (si).
    
 0.984
CAP_3186
Methylaspartate mutase S chain.
  
 0.979
CAP_6601
Glutamate synthase [NADPH] large chain.
    
 0.978
CAP_3199
Malonyl CoA-acyl carrier protein transacylase.
    
 0.975
CAP_5153
Long-chain-fatty-acid--CoA ligase.
  
 
 0.970
CAP_3204
Malonyl CoA-acyl carrier protein transacylase.
    
 0.960
CAP_1007
Acetyl-CoA hydrolase.
 
 
 0.954
CAP_5213
Transcriptional regulator, MerR family.
 
  
 0.950
Your Current Organism:
Chondromyces apiculatus
NCBI taxonomy Id: 1192034
Other names: C. apiculatus DSM 436, Chondromyces apiculatus Cm a2, Chondromyces apiculatus DSM 436, Chondromyces apiculatus str. DSM 436, Chondromyces apiculatus strain DSM 436
Server load: low (26%) [HD]