STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gyrBNegatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (662 aa)    
Predicted Functional Partners:
gyrA
DNA gyrase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.996
parC
DNA topoisomerase IV subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.986
recF
DNA replication/repair protein RecF; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.896
yaaA
RNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.783
dnaN
DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.686
polA
DNA polymerase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.614
smc
Chromosome segregation protein SMC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.565
rpoC
DNA-directed RNA polymerase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.491
metG
methionine--tRNA ligase; MetRS; adds methionine to tRNA(Met) with cleavage of ATP to AMP and diphosphate; some MetRS enzymes form dimers depending on a C-terminal domain that is also found in other proteins such as Trbp111 in Aquifex aeolicus and the cold-shock protein CsaA from Bacillus subtilis while others do not; four subfamilies exist based on sequence motifs and zinc content; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.481
AMB93678.1
ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.478
Your Current Organism:
Aerococcus sanguinicola
NCBI taxonomy Id: 119206
Other names: A. sanguinicola, Aerococcus sanguicola, Aerococcus sanguinicola corrig. Lawson et al. 2001 emend. Tohno et al. 2014, Aerococcus sp. CCUG 43001, CCUG 43001, CIP 106533, DSM 15633, JCM 11549
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