STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ezrASeptation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family. (574 aa)    
Predicted Functional Partners:
divIB
Hypothetical protein; Cell division protein that may be involved in stabilizing or promoting the assembly of the division complex; Belongs to the FtsQ/DivIB family. DivIB subfamily.
  
   
 0.801
KPJ21928.1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.767
KPJ22366.1
Multidrug ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.761
mecA
Adapter protein mecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
  
     0.756
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
 
 0.748
KPJ22946.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.742
KPJ21969.1
Polysaccharide biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.738
KPJ23059.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family.
  
     0.723
KPJ22783.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.711
KPJ21810.1
Helicase loader; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.709
Your Current Organism:
Streptococcus phocae
NCBI taxonomy Id: 119224
Other names: ATCC 51973, CCUG 35103, DSM 15635, LMG 16735, LMG:16735, NCTC 12719, S. phocae, SVL 8399 H1, strain 8399 H1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.