STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A200_03559Amidase; COG1335 Amidases related to nicotinamidase. (210 aa)    
Predicted Functional Partners:
A200_00810
Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family.
 
 0.999
A200_04221
SIR2 family protein; COG0846 NAD-dependent protein deacetylases, SIR2 family.
  
 0.964
A200_02544
COG1957 Inosine-uridine nucleoside N-ribohydrolase.
     
 0.954
A200_05872
COG1957 Inosine-uridine nucleoside N-ribohydrolase.
     
 0.954
A200_08004
Ribonucleoside hydrolase; COG1957 Inosine-uridine nucleoside N-ribohydrolase.
     
 0.954
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
    
 0.856
A200_05722
Gluconate 5-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  
 0.784
A200_02046
Hypothetical protein.
      0.721
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
  
  
 0.714
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.683
Your Current Organism:
Parascardovia denticolens
NCBI taxonomy Id: 1193128
Other names: P. denticolens IPLA 20019, Parascardovia denticolens IPLA 20019, Parascardovia denticolens str. IPLA 20019, Parascardovia denticolens strain IPLA 20019
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