STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A200_07804COG0629 Single-stranded DNA-binding protein. (176 aa)    
Predicted Functional Partners:
dnaE
COG0587 DNA polymerase III, alpha subunit.
   
 0.866
A200_02126
Primosome assembly protein PriA; COG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase.
    
 
 0.781
A200_07799
Hypothetical protein.
       0.773
A200_03162
COG2812 DNA polymerase III, gamma/tau subunits.
    
 
 0.733
A200_03092
DNA polymerase III subunit delta; COG0470 ATPase involved in DNA replication.
    
 
 0.728
rpsF
30S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
  
  
 0.695
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.637
A200_06477
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
 
 0.635
A200_01691
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.633
A200_07634
Hypothetical protein; COG0433 Predicted ATPase.
  
 
 0.588
Your Current Organism:
Parascardovia denticolens
NCBI taxonomy Id: 1193128
Other names: P. denticolens IPLA 20019, Parascardovia denticolens IPLA 20019, Parascardovia denticolens str. IPLA 20019, Parascardovia denticolens strain IPLA 20019
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.