STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH69513.1Putative mannose-6-phosphate isomerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (386 aa)    
Predicted Functional Partners:
CCH70135.1
Putative phosphomannomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.953
pgi
Glucosephosphate isomerase (Glucose-6-phosphate isomerase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
 
 
 0.920
CCH70133.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 0.890
CCH68804.1
Putative phosphomannomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.858
CCH71089.1
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing) (fragment).
     
 0.812
pfp
Pyrophosphate--fructose 6-phosphate 1-phosphotransferase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
     
 0.797
rpe
Ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.
    
 0.794
CCH69047.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the carbohydrate kinase PfkB family.
    
 0.792
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily.
     
 0.780
CCH69393.1
ROK family protein (fragment).
  
 
 0.728
Your Current Organism:
Tetrasphaera elongata
NCBI taxonomy Id: 1193181
Other names: T. elongata Lp2, Tetrasphaera elongata DSM 14184, Tetrasphaera elongata Lp2, Tetrasphaera elongata str. Lp2, Tetrasphaera elongata strain Lp2, actinomycete Lp2
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