STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cysKCysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (309 aa)    
Predicted Functional Partners:
cysE
Serine acetyltransferase.
 
 0.999
metB
Cystathionine gamma-synthase.
 
 0.947
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.943
cysS
Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 0.938
sir
Sulfite reductase (ferredoxin) 2; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
 
 0.934
mshC
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
  
 0.919
metH
homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.916
mccB
Cystathionine gamma-lyase and homocysteine gamma-lyase for reverse transsulfuration pathway; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.894
sseB
Putative thiosulfate sulfurtransferase sseB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.893
CCH71340.1
Cystathionine gamma-synthase.
 
 0.888
Your Current Organism:
Tetrasphaera elongata
NCBI taxonomy Id: 1193181
Other names: T. elongata Lp2, Tetrasphaera elongata DSM 14184, Tetrasphaera elongata Lp2, Tetrasphaera elongata str. Lp2, Tetrasphaera elongata strain Lp2, actinomycete Lp2
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