STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCH70187.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (271 aa)    
Predicted Functional Partners:
CCH70188.1
Hypothetical protein; No homology to any previously reported sequences.
       0.773
CCH68774.1
FAD dependent oxidoreductase; Belongs to the GcvT family.
   
  0.736
CCH70602.1
Putative dehydrogenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family.
   
  0.736
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
  0.645
CCH70328.1
Putative Monooxygenase FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 0.554
CCH70189.1
Hypothetical protein; No homology to any previously reported sequences.
       0.552
wcqE
Putative glycosyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
     0.545
glyA
Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
   
  0.523
CCH69005.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
    0.456
CCH69768.1
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.413
Your Current Organism:
Tetrasphaera elongata
NCBI taxonomy Id: 1193181
Other names: T. elongata Lp2, Tetrasphaera elongata DSM 14184, Tetrasphaera elongata Lp2, Tetrasphaera elongata str. Lp2, Tetrasphaera elongata strain Lp2, actinomycete Lp2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.