STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (406 aa)    
Predicted Functional Partners:
metH
homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.872
CCH71257.1
Putative conserved membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  0.824
CCH70412.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
 0.823
metF
5,10-methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.801
CCH68861.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
  0.799
CCH69145.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
  0.799
CCH69235.1
Putative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  0.799
CCH71168.1
Putative NAD-dependent epimerase/dehydratase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
  0.799
rpe
Ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.
 
 
 
 0.797
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
 
 
 0.748
Your Current Organism:
Tetrasphaera elongata
NCBI taxonomy Id: 1193181
Other names: T. elongata Lp2, Tetrasphaera elongata DSM 14184, Tetrasphaera elongata Lp2, Tetrasphaera elongata str. Lp2, Tetrasphaera elongata strain Lp2, actinomycete Lp2
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