STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (376 aa)    
Predicted Functional Partners:
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
 
 
 0.999
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.973
CCH69577.1
Putative acetyl-coenzyme A synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
   
 
 0.938
CCH69915.1
Putative ferredoxin oxidoreductase (Putative pyruvate synthase (porA)) and gamma subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.890
CCH70582.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 
 0.879
acyP
Acylphosphatase.
     
 0.870
BN10_60005
Acetyl-CoA hydrolase/transferase.
     
 0.778
CCH71541.1
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
 0.776
ilvB
Acetolactate synthase (acetohydroxy-acid synthase) (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.767
CCH69879.1
Putative Acetyl-coenzyme A carboxylase carboxyl transferase subunits beta/alpha; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
  0.767
Your Current Organism:
Tetrasphaera elongata
NCBI taxonomy Id: 1193181
Other names: T. elongata Lp2, Tetrasphaera elongata DSM 14184, Tetrasphaera elongata Lp2, Tetrasphaera elongata str. Lp2, Tetrasphaera elongata strain Lp2, actinomycete Lp2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.