node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCH68774.1 | CCH69310.1 | BN10_1170020 | BN10_1470003 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.966 |
CCH68774.1 | CCH70601.1 | BN10_1170020 | BN10_610012 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.758 |
CCH68774.1 | CCH70602.1 | BN10_1170020 | BN10_610013 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Putative dehydrogenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family. | 0.999 |
CCH68774.1 | cdr | BN10_1170020 | BN10_910007 | FAD dependent oxidoreductase; Belongs to the GcvT family. | CoA-disulfide reductase. | 0.997 |
CCH68774.1 | gcvH | BN10_1170020 | BN10_590007 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.998 |
CCH68774.1 | gcvP | BN10_1170020 | BN10_590002 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.999 |
CCH68774.1 | gltA-2 | BN10_1170020 | BN10_860017 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Glutamate synthase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.965 |
CCH68774.1 | glyA | BN10_1170020 | BN10_1140014 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.930 |
CCH68774.1 | metH | BN10_1170020 | BN10_560064 | FAD dependent oxidoreductase; Belongs to the GcvT family. | homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.977 |
CCH68774.1 | pepPI | BN10_1170020 | BN10_1070024 | FAD dependent oxidoreductase; Belongs to the GcvT family. | Xaa-Pro aminopeptidase 1; Belongs to the peptidase M24B family. | 0.941 |
CCH69310.1 | CCH68774.1 | BN10_1470003 | BN10_1170020 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | FAD dependent oxidoreductase; Belongs to the GcvT family. | 0.966 |
CCH69310.1 | CCH70602.1 | BN10_1470003 | BN10_610013 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative dehydrogenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family. | 0.966 |
CCH69310.1 | gcvH | BN10_1470003 | BN10_590007 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.980 |
CCH69310.1 | gcvP | BN10_1470003 | BN10_590002 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.992 |
CCH69310.1 | gltA-2 | BN10_1470003 | BN10_860017 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glutamate synthase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.967 |
CCH69310.1 | glyA | BN10_1470003 | BN10_1140014 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.910 |
CCH69310.1 | metH | BN10_1470003 | BN10_560064 | Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | homocysteine-N5-methyltetrahydrofolate transmethylase, B12-dependent; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.722 |
CCH70601.1 | CCH68774.1 | BN10_610012 | BN10_1170020 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | FAD dependent oxidoreductase; Belongs to the GcvT family. | 0.758 |
CCH70601.1 | CCH70602.1 | BN10_610012 | BN10_610013 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative dehydrogenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family. | 0.959 |
CCH70602.1 | CCH68774.1 | BN10_610013 | BN10_1170020 | Putative dehydrogenase protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family. | FAD dependent oxidoreductase; Belongs to the GcvT family. | 0.999 |