STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppS-2Undecaprenyl pyrophosphate synthase 1; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (253 aa)    
Predicted Functional Partners:
CCH69836.1
Putative polyprenyl synthase / dimethylallyltranstransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the FPP/GGPP synthase family.
 
 
 0.941
CCH69908.1
Putative polyprenyl diphosphate synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the FPP/GGPP synthase family.
 
 
 0.933
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
     
 0.868
CCH69377.1
Phosphatidate cytidylyltransferase; Belongs to the CDS family.
  
  
 0.841
dxr
1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family.
  
  
 0.834
proS
Prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...]
  
    0.787
CCH69386.1
Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.779
frr
Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.
  
  
 0.771
uppS
Undecaprenyl pyrophosphate synthase 2; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
  
 
0.761
rimP
Ribosome maturation factor rimP; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family.
  
    0.741
Your Current Organism:
Tetrasphaera elongata
NCBI taxonomy Id: 1193181
Other names: T. elongata Lp2, Tetrasphaera elongata DSM 14184, Tetrasphaera elongata Lp2, Tetrasphaera elongata str. Lp2, Tetrasphaera elongata strain Lp2, actinomycete Lp2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.