STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrDDihydroorotate dehydrogenase (catalytic subunit); Catalyzes the conversion of dihydroorotate to orotate. (342 aa)    
Predicted Functional Partners:
BN11_10043
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
 0.999
BN11_30020
Dihydroorotate dehydrogenase electron transfer subunit.
 
 0.999
BN11_60004
Sulfide dehydrogenase (Flavoprotein) subunit SudB / sulfide dehydrogenase (Flavoprotein) subunit SudA.
 0.998
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.
 
 0.996
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 0.991
pyrF
Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.989
pyrB
Aspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 
 0.982
gltA
Glutamate synthase (NADPH), homotetrameric.
 0.981
pyrR
Bifunctional protein pyrR (Includes: Pyrimidine operon regulatory protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant.
  
 
 0.981
pyrAB
Pyrimidine-specific carbamoyl-phosphate synthetase (large subunit); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
 
 0.979
Your Current Organism:
Tetrasphaera australiensis
NCBI taxonomy Id: 1193182
Other names: T. australiensis Ben110, Tetrasphaera australiensis Ben110, Tetrasphaera australiensis str. Ben110, Tetrasphaera australiensis strain Ben110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.