STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dfrADihydrofolate reductase. (169 aa)    
Predicted Functional Partners:
thyA1
Thymidylate synthase 1.
 
 
 0.998
fgs
Folylpolyglutamate synthase.
     
 0.864
glyA
Pyridoxal-phosphate-dependent serine hydroxymethyltransferase.
  
 
 0.854
fhs
Formate--tetrahydrofolate ligase.
  
 
 0.847
fmt
Methionyl-tRNA formyltransferase.
  
 
 0.846
metH
Methionine synthase.
    
 0.843
purH
Bifunctional purine biosynthesis protein PurH.
    
 0.841
purN
Phosphoribosylglycinamide formyltransferase.
   
 
 0.841
aroE
Shikimate dehydrogenase.
    
 0.693
tmk
Thymidylate kinase.
    
 0.595
Your Current Organism:
uncultured Flavonifractor sp.
NCBI taxonomy Id: 1193534
Other names: u. Flavonifractor sp.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.