SHF80223.1 protein (Aliifodinibius roseus) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Coexpression

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[Homology]

Score

SHF80223.1

Plastocyanin. (151 aa)

Predicted Functional Partners:

SHF80101.1

0.794

SHF80142.1

0.774

SHF80182.1

0.773

SHF79983.1

0.761

SHG11098.1

0.523

SHF12185.1

0.468

SHF97946.1

0.468

SHG39692.1

0.468

SHF80266.1

0.443

SHE94166.1

0.434

Your Current Organism:

Aliifodinibius roseus

NCBI taxonomy Id: 1194090
Other names: A. roseus, ACCC 10715, Aliifodinibius roseus Wang et al. 2013, Bacteroidetes bacterium YIM D15, DSM 21986, KCTC 23442, YIM D15

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SHE94166.1	SHF12185.1	SAMN05443144_104154	SAMN05443144_105227	Cytochrome c.	Copper-resistance protein, CopA family.	0.638
SHE94166.1	SHF79983.1	SAMN05443144_104154	SAMN05443144_11394	Cytochrome c.	Dissimilatory nitrite reductase (NO-forming), copper type apoprotein.	0.986
SHE94166.1	SHF80101.1	SAMN05443144_104154	SAMN05443144_11397	Cytochrome c.	Nitrite reductase (NO-forming).	0.638
SHE94166.1	SHF80182.1	SAMN05443144_104154	SAMN05443144_11399	Cytochrome c.	Protein SCO1/2.	0.913
SHE94166.1	SHF80223.1	SAMN05443144_104154	SAMN05443144_113100	Cytochrome c.	Plastocyanin.	0.434
SHE94166.1	SHF97946.1	SAMN05443144_104154	SAMN05443144_11661	Cytochrome c.	Copper-resistance protein, CopA family.	0.638
SHE94166.1	SHG11098.1	SAMN05443144_104154	SAMN05443144_11940	Cytochrome c.	Nitrite reductase (NADH) small subunit.	0.583
SHE94166.1	SHG39692.1	SAMN05443144_104154	SAMN05443144_1275	Cytochrome c.	Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA).	0.638
SHF12185.1	SHE94166.1	SAMN05443144_105227	SAMN05443144_104154	Copper-resistance protein, CopA family.	Cytochrome c.	0.638
SHF12185.1	SHF80223.1	SAMN05443144_105227	SAMN05443144_113100	Copper-resistance protein, CopA family.	Plastocyanin.	0.468
SHF79983.1	SHE94166.1	SAMN05443144_11394	SAMN05443144_104154	Dissimilatory nitrite reductase (NO-forming), copper type apoprotein.	Cytochrome c.	0.986
SHF79983.1	SHF80142.1	SAMN05443144_11394	SAMN05443144_11398	Dissimilatory nitrite reductase (NO-forming), copper type apoprotein.	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain.	0.788
SHF79983.1	SHF80182.1	SAMN05443144_11394	SAMN05443144_11399	Dissimilatory nitrite reductase (NO-forming), copper type apoprotein.	Protein SCO1/2.	0.773
SHF79983.1	SHF80223.1	SAMN05443144_11394	SAMN05443144_113100	Dissimilatory nitrite reductase (NO-forming), copper type apoprotein.	Plastocyanin.	0.761
SHF79983.1	SHG11098.1	SAMN05443144_11394	SAMN05443144_11940	Dissimilatory nitrite reductase (NO-forming), copper type apoprotein.	Nitrite reductase (NADH) small subunit.	0.571
SHF80101.1	SHE94166.1	SAMN05443144_11397	SAMN05443144_104154	Nitrite reductase (NO-forming).	Cytochrome c.	0.638
SHF80101.1	SHF80142.1	SAMN05443144_11397	SAMN05443144_11398	Nitrite reductase (NO-forming).	Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain.	0.901
SHF80101.1	SHF80182.1	SAMN05443144_11397	SAMN05443144_11399	Nitrite reductase (NO-forming).	Protein SCO1/2.	0.872
SHF80101.1	SHF80223.1	SAMN05443144_11397	SAMN05443144_113100	Nitrite reductase (NO-forming).	Plastocyanin.	0.794
SHF80101.1	SHF80266.1	SAMN05443144_11397	SAMN05443144_113101	Nitrite reductase (NO-forming).	Azurin.	0.497

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

25

PPI enrichment p-value:

7.3e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 92

1.32

2.29

4.91e-12

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019843

rRNA binding

10 of 37

1.68

3.81

1.21e-13

GO:0003735

Structural constituent of ribosome

10 of 49

1.56

3.21

7.30e-13

GO:0000049

tRNA binding

5 of 19

1.67

2.13

6.14e-06

GO:0003676

Nucleic acid binding

11 of 225

0.93

1.11

6.14e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044391

Ribosomal subunit

6 of 12

1.94

3.67

2.03e-09

GO:0005840

Ribosome

10 of 53

1.52

3.08

7.12e-13

GO:0015935

Small ribosomal subunit

3 of 6

1.94

1.87

0.00015

GO:0015934

Large ribosomal subunit

3 of 6

1.94

1.87

0.00015

GO:0005622

Intracellular anatomical structure

11 of 682

0.45

0.39

0.00015

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:64

Ribosome, and Translational elongation

11 of 72

1.43

2.78

1.87e-13

CL:68

Ribosome, and Elongation factor

9 of 61

1.41

2.45

1.49e-10

CL:72

Ribosome

5 of 28

1.5

1.8

1.36e-05

CL:154

rRNA binding, and Elongation factor Tu GTP binding domain

4 of 18

1.59

1.68

9.76e-05

CL:75

Ribosome

4 of 22

1.51

1.5

0.00019

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

10 of 52

1.53

3.13

5.28e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0044391

Ribosomal subunit

6 of 15

1.85

3.0

6.83e-08

GOCC:0015934

Large ribosomal subunit

4 of 6

2.07

2.65

3.45e-06

GOCC:0005840

Ribosome

7 of 36

1.53

2.37

6.83e-08

GOCC:0022626

Cytosolic ribosome

4 of 10

1.85

2.23

1.26e-05

GOCC:0043229

Intracellular organelle

10 of 171

1.01

1.22

6.83e-08

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

10 of 52

1.53

3.1

8.99e-13

KW-0687

Ribonucleoprotein

10 of 52

1.53

3.1

8.99e-13

KW-0820

tRNA-binding

4 of 10

1.85

2.17

1.77e-05

KW-0699

rRNA-binding

6 of 31

1.53

2.15

7.32e-07

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