STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHG23699.1uroporphyrinogen-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (273 aa)    
Predicted Functional Partners:
SHG23765.1
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
 
 0.998
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.994
SHG23670.1
Sulfite reductase (ferredoxin); Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.957
cysH
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.941
SHE76557.1
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.931
SHG11361.1
uroporphyrinogen-III synthase.
 
 
 0.795
hemL
Glutamate-1-semialdehyde 2,1-aminomutase.
 
  
 0.788
SHE60895.1
Sirohydrochlorin ferrochelatase.
  
 
 0.775
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.764
SHG27836.1
Phosphoadenylylsulfate reductase (thioredoxin); Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
 
  
 0.751
Your Current Organism:
Aliifodinibius roseus
NCBI taxonomy Id: 1194090
Other names: A. roseus, ACCC 10715, Aliifodinibius roseus Wang et al. 2013, Bacteroidetes bacterium YIM D15, DSM 21986, KCTC 23442, YIM D15
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